在日本治疗创伤后应激障碍的认知处理疗法:一项随机临床试验
Masaya Ito1, Akiko Katayanagi1,2, Mitsuhiro Miyamae1
1National Center for Cognitive Behavior Therapy and Research, National Center of Neurology and Psychiatry, Tokyo, Japan.
JAMA network open
|February 5, 2025
概括
认知处理疗法 (CPT) 有效地减少了日本门诊患者的创伤后应激障碍 (PTSD) 症状. 这项研究为CPT提供了关键证据.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 创伤研究 创伤研究
背景情况:
- 认知处理疗法 (CPT) 是对创伤后应激障碍 (PTSD) 的一项成熟治疗方法.
- 关于CPT在东亚人群中的疗效的证据有限.
- 需要评估CPT在非西方临床环境中的有效性.
研究的目的:
- 评估CPT与常规治疗 (CPT-TAU) 结合治疗的有效性,与等待名单与常规治疗 (WL-TAU) 相比,对日本的PTSD门诊患者.
- 为了确定CPT是否可以在日本医疗背景下减少PTSD症状.
主要方法:
- 进行了一项为期16周的单中心,评估者盲目的,并行组随机临床试验.
- 被诊断患有PTSD的成人门诊患者是从东京国家精神病学转诊医院招募的.
- 参与者被随机分配到CPT-TAU (12周一次会议) 或WL-TAU.
主要成果:
- 在CPT-TAU组中,PTSD症状显著减少,通过临床医生管理的PTSD尺度 (CAPS-5) 来衡量.
- CPT-TAU在所有次要结果中表现出优越性,包括抑郁症,自杀念头和残疾.
- 与WL-TAU组相比,CPT-TAU组的中断率很低,没有严重的不良事件.
结论:
- CPT,当提供通常的治疗时,有效地减少了日本环境中的门诊患者中PTSD症状.
- 这些发现支持CPT在东亚人口中的更广泛应用.
- 这项研究加强了CPT作为全球PTSD可行的治疗选择的证据基础.
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