患有缺乏症的糖尿病患者的临床结果:一项多机构基于人口的研究
Jheng-Yan Wu1,2, Yu-Jou Wu3, Mei-Yuan Liu1,4,5,6
1Department of Nutrition, Chi Mei Medical Center, Tainan, Taiwan.
Journal of the American Nutrition Association
|February 5, 2025
概括
糖尿病患者的缺乏症显著增加死亡,心血管事件,事件和住院的风险. 监测水平对于管理糖尿病并发症至关重要.
科学领域:
- 内分泌学和新陈代谢学
- 心血管医学 心血管医学
- 腎臟病學 (nephrology) 是一種醫學.
背景情况:
- 糖尿病是一种复杂的代谢障碍,与许多并发症有关.
- 缺乏 (ZD) 越来越被认为是各种慢性疾病不良结果的潜在因素.
研究的目的:
- 为了研究缺乏和糖尿病患者的不良健康结果之间的联系.
- 评估ZD对所有原因死亡率,主要不良心血管事件 (MACE),主要不良事件 (MAKE) 和所有原因住院治疗的影响.
主要方法:
- 使用TriNetX研究网络进行的回顾性队列研究.
- 包括2010年1月1日至2024年8月31日期间患有DM的成年患者.
- 倾向性得分匹配与ZD患者 (血清<70μg/dL) 与对照患者 (血清70-120μg/dL) 的比较.
主要成果:
- 每组有11,698名匹配患者,具有平衡的基线特征.
- 在1年的随访期间,ZD组的死亡率 (HR: 1.788),MACE (HR: 1.641) 和MAKE (HR: 1.534) 的风险显著增加.
- 在ZD组中观察到全因住院的风险增加 (HR: 1.272).
结论:
- 缺乏与糖尿病患者死亡率,MACE,MAKE和住院住院的风险增加有关.
- 这些发现凸显了在糖尿病护理中评估和管理状况的临床重要性.
- 进一步的研究可能会探索针对DM管理中的水平的治疗干预措施.
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