口腔癌:一个全面的系统审查和元分析
Caio Vinícius Suartz1,2, Lucas Motta Martinez3, Marcelo Henrique Lima Silvestre3
1Department of Urology, Northern Ontario School of Medicine, Thunder Bay, Ontario, Canada.
概括
这份综述强调,在 urachal carcinoma 治疗中,带切除的 en-bloc 切除是有利的,基于 cisplatin 的化学疗法显示出有效性. 五年生存率为51%,复发影响35%的患者.
科学领域:
- 在瘤学瘤学.
- 尿道瘤学 尿道瘤学
- 手术瘤学手术瘤学
背景情况:
- 口腔癌是一种罕见的恶性瘤,现有数据有限.
- 巩固诊断,流行病学和治疗方面的证据对于改善患者的治疗结果至关重要.
研究的目的:
- 系统地审查和元分析关于 urachal 癌症的当前证据.
- 评估诊断策略,治疗方法和瘤学结果.
主要方法:
- 在PubMed/MEDLINE系统搜索到2024年9月.
- 包括50项研究,包括1,901例 urachal 癌症.
- 单臂元分析以评估瘤学结果.
主要成果:
- 在局部疾病中,带切除的En-bloc切除证明了瘤的优势.
- 基于西斯普拉丁的化疗在辅助和转移环境中显示出最佳反应.
- 估计的5年总生存率为51%;瘤复发在35%的病例中.
结论:
- 本综述为 urachal carcinoma 的临床决策提供了全面的证据.
- 建议使用切除术和特定化疗进行En-bloc切除.
- 需要进一步研究替代疗法,以优化患者的治疗结果.
更多相关视频
09:28Patient-derived Orthotopic Xenograft Models for Human Urothelial Cell Carcinoma and Colorectal Cancer Tumor Growth and Spontaneous Metastasis
Published on: May 12, 2019
10.1K
06:39Technical Modification of the Terminal Ureter During Total Transperitoneal Laparoscopic Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma
Published on: November 22, 2019
7.6K
相关概念视频
Cancer
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
Assessment of the Mouth
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
Cancer Survival Analysis
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
