多模式适应呼吸道肌肉向阻力训练:在健康的年轻成年人的初步研究
Rahul Krishnamurthy1,2, Douglas H Schultz3,4, Yingying Wang2,3
1Department of Neurosurgery, University of Nebraska Medical Center, Omaha.
Journal of speech, language, and hearing research : JSLHR
|February 5, 2025
概括
在健康的成年人中,呼吸道肌肉强度训练 (EMST) 增加了最大呼吸道压力和脑衍生神经营养因子 (BDNF). 这表明EMST可能会促进神经可塑性并增强功能强度.
科学领域:
- 神经科学是一个神经科学.
- 运动生理学 运动生理学
- 语言和吞科学 语言和吞科学
背景情况:
- 神经可塑性在骨肌肉炼中得到了充分证实,但人们对言语和吞练习知之甚少.
- 针对呼吸道肌肉的阻力训练 (EMST) 为研究神经可塑性潜力提供了一种新的方法.
研究的目的:
- 为了评估与神经可塑性相关的分子和功能变化,从健康年轻人的4周EMST计划中评估.
- 收集关于EMST对神经营养因子和大脑活动的影响的初步数据.
主要方法:
- 五名健康的男性 (19-35岁) 完成了4周的EMST.
- 测量包括最大呼气压 (MEP),血清脑衍生神经营养因子 (BDNF) 和胰岛素样生长因子1 (IGF-1) 在基线和训练后.
- 用功能和结构MRI扫描来评估神经可塑性变化.
主要成果:
- 训练后观察到MEP和血清BDNF水平的显著增加.
- 在IGF-1水平上没有发现显著的变化.
- 功能性MRI显示八个大脑区域的激活增加,但白质微观结构没有显著变化.
结论:
- 通过EMST诱导分子和神经可塑性适应,与骨肌肉炼相当.
- EMST显示出作为调节神经营养信号通路的干预措施的潜力.
- 这些适应可能与功能强度增加和神经可塑性增强有关.
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