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在看起来健康的婴儿中,结果最初推迟了用于发烧的抗生素
Emily Willey1, Tracy Zembles2, Elizabeth Segar3
1Children's Wisconsin, Milwaukee, Wisconsin, emilyrwilley@gmail.com.
推迟抗生素治疗22-60天的发烧的婴儿,减少了抗生素的使用和腰部穿刺. 这种做法没有增加侵袭性细菌感染或需要升级护理的需求,支持当前的指南.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 临床实践指南 临床实践指南
背景情况:
- 2021年美国儿科学会的指导方针建议在某些发烧的婴儿 (22-60天) 中推迟抗生素和腰部穿刺.
- 在这些情况下,建议与护理人员共同做出决策.
研究的目的:
- 为了比较入侵性细菌感染 (IBI) 的发生率和发烧婴儿 (22-60天) 在实施指南之前和之后的护理升级.
- 评估推迟初始实证抗生素对患者结果的影响.
主要方法:
- 一个单一中心的回顾性队列研究评估了入院的婴儿 (22-60天) 符合发烧指南标准.
- 结果包括IBI的发病率,护理升级,阳性细菌培养,停留时间和死亡率.
- 数据是在指导方针实施之前和之后收集的.
主要成果:
- 在前指南和后指南组 (21vs40名患者) 之间没有观察到IBI发生率或护理升级的显著差异.
- 阳性细菌培养率,停留时间和死亡率保持相似.
- 在指南后的组中,进行的腰部穿刺较少.
结论:
- 在看起来健康的发烧婴儿 (22-60天) 中推迟抗生素服用符合指导方针建议.
- 这种方法可以降低抗生素暴露率和腰部穿刺率,而不会影响患者在IBI或护理升级方面的安全性.
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