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Updated: May 29, 2025

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峰表媒通过Sirt1的二基化,通过对抗CYLD的NF-kB激活来缓解类风湿性关节炎

Zhiming Wu1, Peng Zhang1, Wenyan Huang2

  • 1Chinese Medicine Department, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330000, Jiangxi Province, PR China.

Immunobiology
|February 5, 2025
PubMed
概括

昆 (Qufeng) (epimedium) 疗法通过减少炎症和细胞死亡来治疗类风湿性关节炎 (RA). 它通过通过CYLD稳定Sirt1,抑制NF-kB/GSDMD通路而起作用.

关键词:
缓解纤维细胞样同胞细胞灭症.这就是CYLDLD的意义.峰中介的开制剂 .类风湿性关节炎 类风湿性关节炎 类风湿性关节炎在Sirt1上

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The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
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