作为化疗免疫治疗剂的二利登和皮佩里结合 (IV) 复合物的设计,合成和评估

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Zhi-Chen Mao1, Lei Chen1, Xiao-Man Chen1

  • 1Guangxi Key Laboratory of Drug Discovery and Optimization, School of Pharmacy, Guilin Medical University, 541199, Guilin, Guangxi, China; Guangxi Engineering Research Center for Pharmaceutical Molecular Screening and Druggability Evaluation, School of Pharmacy, Guilin Medical University, 541199, Guilin, Guangxi, China.

European journal of medicinal chemistry
|February 5, 2025
PubMed
概括

新的 (IV) 复合物结合了STAT3抑制剂和氧沙,显示出对癌细胞和瘤有强大的化疗免疫疗效. 这些药物表现出显著的疗效和减少毒性比oxaliplatin,表明他们的潜力作为新的癌症治疗药物.

关键词:
化学免疫治疗剂 化学免疫治疗剂铁性化 (ferroptosis) 是一种氧化酸是一种氧化酸.在STAT3中,我们可以使用STAT3.一个T细胞细胞.

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