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Updated: May 29, 2025

The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions
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开发基于多酶级联系统的电化学生物传感器的协同优化策略,以提高性能

Yuzhuo Zhu1, Zhaoming Cheng2, Xueqi Wang2

  • 1Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, PR China; Tianjin Key Laboratory of Intelligent and Green Pharmaceuticals for Traditional Chinese Medicine, Tianjin, 301617, PR China.

Biosensors & bioelectronics
|February 5, 2025
PubMed
概括

多酶级联系统 (MCS) 通过结合多种酶来增强电化学生物传感器. 本综述详细介绍了MCS策略,优化技术以及改善生物传感应用中的灵敏度和稳定性的未来方向.

关键词:
级联反应是一种级联反应.电化学生物传感器酶式生物传感器是一种生物传感器.多酶系统 多酶系统协同作用的战略 协同作用的战略

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When a ligand binds to a cell-surface receptor, the receptor's intracellular domain changes shape, which may either activate its enzyme function or allow its binding to other molecules. The initial signal is amplified by most signal transduction pathways. This means that a single ligand molecule can activate multiple molecules of a downstream target. Proteins that relay a signal are most commonly phosphorylated at one or more sites, activating or inactivating the protein. Kinases catalyze...
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