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Updated: Aug 10, 2026

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在活体中对小鼠T细胞进行工程,使用进化的腺相关病毒变体Ark31313进行工程

William A Nyberg1, Charlotte H Wang2, Jonathan Ark3

  • 1Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA.

Immunity
|February 5, 2025
PubMed
概括

研究人员开发了Ark313,一种人工基关联病毒 (AAV) 囊体,用于有效地进行小鼠T细胞的体内基因工程. 这一突破使得精确的T细胞操纵能够研究免疫反应和推进免疫疗法.

关键词:
在 AAV AAV AAV 中.在Ark31313中,我们可以看到Ark313的标志.在T细胞工程方面,T细胞工程基因向是指基因的向.免疫疗法是一种免疫疗法.在体内生产的交付.在体内进行基因编辑.在敲门的时候.鼠标T细胞 鼠标T细胞

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