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Updated: May 6, 2026

An Ex Vivo Laser-induced Spinal Cord Injury Model to Assess Mechanisms of Axonal Degeneration in Real-time
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针对Ca2+储存介导的Ca2+释放和储存操作的进入的联合治疗减少了二次轴突退化,并改善了SCI后的功能结果

Emma Jones1, Spencer O Ames1, Jesse Brooks1

  • 1Kentucky Spinal Cord Injury Research Center, University of Louisville School of Medicine, Louisville, KY 40202, USA.

Experimental neurology
|February 5, 2025
PubMed
概括

通过STIM1/Orai解和IP3R抑制抑制储存运行的入 (SOCE),可以改善脊髓损伤 (SCI) 后的神经恢复和轴突生存. 这种新的治疗方法针对二次轴突退化,以获得更好的结果.

关键词:
轴突退化 轴突退化亚克索等离子体网络.IP (((R3)) 的意思是这里是Orai Orai.脊髓损伤导致的脊髓损伤储存运行的入口 (SOCE)流体相互作用分子蛋白 (STIM)

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