对于患者的tDCS的安全性和有效性:系统性审查和元分析
Xiao-Tong Ding1, Ming-Yu Hu2, Chi Wang2
1Kiang Wu Nursing College of Macau, Macau SAR, China.
Complementary therapies in medicine
|February 5, 2025
概括
跨直流刺激 (tDCS) 有效地减少了患者的发作频率. 然而,目前的证据不支持其用于性发作,抑郁,焦虑或认知功能的改善.
科学领域:
- 神经学 神经学
- 神经科学是一个神经科学.
- 医疗器械 医疗器械
背景情况:
- 跨直流刺激 (tDCS) 在管理中有着悠久的使用历史.
- 需要进一步的研究来确定tDCS在治疗中的有效性和安全性.
研究的目的:
- 系统地审查和元分析tDCS在治疗方面的有效性.
- 为了评估tDCS对发作频率,型出血,抑郁,焦虑和认知功能的影响.
主要方法:
- 在主要的科学数据库 (科克莱恩图书馆,PubMed,Embase,Scopus,Web of Science) 进行了全面的搜索.
- 包括356名参与者的12项试验,分析了发作频率,型出血,认知功能,抑郁,焦虑和不良事件.
- 使用Review Manager 5.4软件进行的元分析.
主要成果:
- tDCS 显示了发作频率的显著降低 (SMD = -0.63,P < 0.00001).
- 在tDCS和假装组之间没有观察到型分泌或不良事件的显著差异.
- tDCS对抑郁和焦虑产生不一致的影响,对认知功能没有影响.
结论:
- tDCS有效降低患者的发作频率.
- 目前的证据不足以支持tDCS改善型出血,抑郁,焦虑或认知功能.
- 未来的研究应该专注于标准化协议,个性化,方法严谨性和长期影响.
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