改善药物安全的数字卫生技术干预措施:经济评估的系统审查
Widya Norma Insani1,2, Neily Zakiyah1,2, Irma Melyani Puspitasari1,2
1Department of Pharmacology and Clinical Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia.
数字健康技术 (DHT) 的干预措施具有成本效益,可以提高药物安全性,显著减少不良药物事件 (ADEs) 和药物错误. 这些技术在3至4.25年内提供了强的投资回报.
科学领域:
- 医疗信息学 医疗信息学
- 药物经济学 药物经济学
- 患者安全 患者安全
背景情况:
- 与药物相关的危害,包括药物不良事件 (ADEs) 和药物错误,造成了严重的阳性负担.
- 数字健康技术 (DHT) 干预措施在提高药物安全性方面显示出有前景.
- 与其临床有效性相比,对DHT对药物安全性的成本效益仍然不太了解.
研究的目的:
- 系统地审查DHT干预措施对药物安全的经济影响.
- 识别和检查现有研究中的方法挑战.
- 为这个领域的未来研究方向提供信息.
主要方法:
- 在PubMed,Scopus和EBSCOhost数据库中进行了系统的文献搜索.
- 遵循PRISMA系统审查指南和卫生和医学成本效益小组关于数据提取的建议.
- 采用叙事分析来综合临床和经济结果,根据CHEERS指南评估报告质量.
主要成果:
- 包括13项评估DHT药物安全性成本效益 (n=9),成本效益 (n=3) 和成本效益 (n=1) 的研究.
- 超过一半的研究 (n=7) 集中在临床决策支持系统 (CDSS) /计算机化提供者订单输入 (CPOE) 上.
- 在92.3%的研究中,DHT被发现具有成本效益或成本效益,减少了37.12%的ADEs和54.38%的错误.
结论:
- 数字健康技术干预措施在经济上是可行的,可以提高药物安全性.
- DHT显著减少不良药物事件和药物错误,在3至4.25年内显示出投资回报.
- 未来的研究应该包括警报合规跟踪,ADE/错误严重程度分类,以及间接成本评估,以提高临床和经济效益.
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