重新审视眼球角膜炎住院诊断查的实用性:一项八年后期研究
Paras P Shah1, Daniel Barmas-Alamdari1, Hannah Yoo1
1Department of Ophthalmology, Manhattan Eye, Ear and Throat Hospital, New York, New York, USA.
Ocular immunology and inflammation
|February 5, 2025
概括
住院患者的眼球角膜炎查很少产生积极的结果,即使是Candidemia. 早期的抗真菌治疗往往限制了眼科咨询的诊断价值,这表明需要修订协议.
科学领域:
- 眼科医生 眼科 眼科
- 传染性疾病 传染性疾病
- 医学真菌学 医学真菌学
背景情况:
- 住院眼球疹查旨在检测严重的真菌感染.
- 美国眼科学会 (AAO) 和美国传染病学会 (IDSA) 的当前指南可能会从重新评估中受益.
- 了解查效用对于优化患者护理和资源配置至关重要.
研究的目的:
- 重新评估入院患者眼球疹查的实用性.
- 评估随后的干预措施和入院患者怀疑眼球疹病的结果.
- 引导AAO和IDSA关于查和管理的指导方针之间的协调.
主要方法:
- 在两个高等保健中心进行了回顾性队列研究 (2017-2024年).
- 纳入标准:阳性Candida培养物或相关的ICD-10代码.
- 收集的数据:培养结果,精神状态,视力敏度,眼部症状,全身抗真菌使用,扩张 fundus 检查 (DFE) 发现,免疫功能受损状态和干预措施.
主要成果:
- 在897次接触中,285次 (31.8%) 咨询了眼球疹病.
- 大多数咨询 (74.4%) 显示不显著的DFE.
- 在免疫受损和免疫能力较强的组之间,或症状和无症状组之间,在DFE阳性度上没有统计学上显著的差异. 没有进行过眼科指导的干预.
- 罕见的诊断: 3.2% 坎迪达视网膜炎, 0.4% 坎迪达内.
结论:
- 在住院患者中,即使是Candidemia,Candida内和视网膜炎也是罕见的.
- 在眼科咨询之前经验性抗真菌治疗限制了诊断产量.
- 需要进行进一步的研究,以制定早期检测和预防严重后果的协议,同时优化资源使用.
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