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直接口服青素的经济评估挑战取消标签的低风险患者与青素过敏标签的挑战

R Bestwick¹, R Bhogal², K Kildonaviciute³

¹Academic Unit of Health Economics, Leeds Institute of Health Sciences, University of Leeds, Leeds, UK.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

|February 5, 2025

概括

通过直接口服青素挑战 (DPC) 删除不准确的青素过敏标签 (PAL) 是昂贵的. 没有发现短期节省,急性护理机构的费用更高,因为青素过敏脱标 (PADL).

科学领域:

卫生经济学卫生经济学
传染性疾病传染性疾病
抗微生物药物管理委员会

背景情况:

不准确的青素过敏标签 (PAL) 导致不必要的广泛抗生素使用,导致抗菌素耐药性.
建立由非专家领导的有效的青素过敏取消标签 (PADL) 服务至关重要.
确定最佳的PADL服务模式对于有效的抗生素管理至关重要.

研究的目的:

确定英国国家卫生服务部门为PALs的低风险患者提供直接口服青素挑战 (DPC) 的成本.
为了比较三个非过敏专家领导的PADL模型的成本:药剂师领导,护士领导和混合多学科.
模拟取消标签对医疗保健利用的长期影响.

主要方法:

对DPC途径的成本分析,包括员工时间和抗生素资源.
使用文献数据,在5年内模拟取消标签对医疗保健利用的影响.
在不同医院部门和分娩模式中比较每位被取消标签的患者的成本.

主要成果:

在2257名查患者中,有126人接受了DPC,其中122人成功取消了标签.
DPC途径的成本从总途径成本的15% (护士领导) 到23% (药剂师领导,混合) 变化.
每位被取消标签的患者的成本从577英 (血液学瘤学,护士领导) 到2329英 (AMU/IDU,护士领导).

结论:

素过敏脱标途径的整体成本至少是单独DPC成本的4倍.
与可选设置相比,急性护理设置的成本明显高 (高达3倍).
在本研究中,从主动或机会主义的PADL中没有发现短期成本节约.

关键词:

经过成本分析,分析成本.直接的口服青素挑战卫生经济学卫生经济学低风险的低风险是什么青素过敏青素过敏风险分层的风险分层.

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