支持患有癌症的老年人和他们的支持者,通过老年评估和远程炼和教育:SOAR研究协议
Nirusha Jebanesan1, Shabbir M H Alibhai2, Daniel Santa Mina3
1Lawrence Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.
Journal of geriatric oncology
|February 5, 2025
概括
这项研究测试了一项计划,将老年评估和管理 (GAM) 与基于虚拟椅子的运动 (CBE) 结合起来,并为患癌症的脆弱老年人提供教育. 这种干预是可行的和可以接受的,显示了在癌症治疗期间改善幸福感的希望.
科学领域:
- 老年瘤学 老年瘤学
- 运动科学 运动科学
- 癌症康复 癌症康复
背景情况:
- 接受癌症治疗的脆弱老年人面临着严重的不良结果风险.
- 运动是有益的,但很少有研究针对癌症的脆弱老年人和他们的支持人员.
- 综合老年评估 (GA) 与运动干预尚未探索.
研究的目的:
- 确定结合老年医学评估和管理 (GAM) 加上虚拟椅式运动 (CBE) 和健康教育计划的可行性和可接受性.
- 评估这项针对癌症的脆弱老年人和他们的支持人员的干预措施.
- 收集数据来设计未来的第三阶段临床试验.
主要方法:
- 一个2期随机对照试验,涉及70岁以上的患有特定癌症的患者,接受化疗,免疫疗法或向治疗.
- 参与者是脆弱的,久坐不动的,并随机分为1:1GAM+在线CBE和健康教育12周或等候名单对照.
- 支持人员与老年人一起参加了同一个干预组.
主要成果:
- 主要终点集中在招聘率,留守率,遵守率和收集数据以评估可行性和可接受性.
- 二次结果指标包括身体活动,功能,疲劳,生活质量,治疗毒性和住院次数.
- 为第三阶段试验设计获得了初步效果大小估计.
结论:
- 该研究将调查GAM加CBE和健康教育的可行性和可接受性.
- 它旨在获得初步结果估计,以防止功能衰退和改善生活质量.
- 结果将为最终的第三阶段随机对照试验的设计提供信息.
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