更好的转录基因稳定性和更广泛的转录基因热响应范围推动了全球侵入性海相对于本地海的更大热耐受性
Changyi Zhang1, Shufen Jiang1, Kenneth B Storey2
1Research Center of Herpetology, College of Life Science, Nanjing Normal University, Nanjing, China.
Integrative zoology
|February 6, 2025
概括
侵袭性海由于更稳定的转录组和在热应激下增强的生存机制,表现出更大的耐热性. 这项研究有助于了解入侵动态,并预测未来的入侵物种.
科学领域:
- 生态生态学 生态生态学
- 进化生物学 进化生物学
- 环境科学 环境科学
背景情况:
- 侵入性物种往往具有更大的耐热性,在极端气候事件和全球变暖期间有助于生存.
- 了解入侵物种和本地物种之间的热耐受性之间的跨物种差异对于预测入侵成功至关重要.
研究的目的:
- 研究分子机制,特别是全球转录组学和抗氧化剂防御,这是侵袭性红耳滑鼠 (Trachemys scripta elegans) 和中国本土的条纹 (Mauremys reevesii) 之间的潜在热耐受性差异.
- 为了将这些分子反应与在幼中观察到的热极限差异联系起来.
主要方法:
- 在不同温度范围内对T. scripta elegans和M. reevesii的全球转录组学和抗氧化酶活性进行比较分析.
- 基因表达模式和生理反应与特定物种的热耐受性极限的相关性.
主要成果:
- 这两种物种都对热应激有着保存的转录反应,包括蛋白质折叠,DNA修复,细胞循环调节和细胞亡.
- 侵袭性T. scripta elegans在热应激下表现出更稳定的转录组,在更广泛的热范围内持续上调蛋白质折叠和亡抑制机制.
- 与极端高温下生存机制相关的基因的不同趋势表明这两种物种之间的能量周转率存在差异.
结论:
- 侵入性乌的更高的耐热性与更强壮和更适应性的转录组有关,特别是在维持蛋白质平衡和调节亡方面.
- 这些发现为成功入侵的生理基础提供了洞察力,并可以在不断变化的气候条件下对未来入侵物种的预测提供信息.
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