对慢性骨盆疼痛综合征的同时治疗的评估
Reza Valipour1, Behzad Narouie2, Arash Rastgou1
1Islamic Azad University of Medical Sciences, Tehran Branch, Tehran, Iran.
Urologia
|February 6, 2025
概括
这项研究发现,将坦苏洛辛,莱沃素和塞莱科克西布结合使用,可为42.7%的患有慢性前列腺炎/慢性骨盆疼痛综合征 (CP/CPPS) 的男性提供疼痛缓解. 年龄和吸烟等因素影响了治疗结果.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 药理学 药理学是指药理学的学科.
- 疼痛管理 疼痛管理
背景情况:
- 慢性前列腺炎/慢性盆腔疼痛综合征 (CP/CPPS) 是一种普遍且具有挑战性的疾病,缺乏明确的治疗共识.
- 没有先前的研究研究了tamsulosin,levofloxacin和celecoxib在男性中治疗CP/CPPS的联合疗效.
研究的目的:
- 为了评估治疗对tamsulosin,levofloxacin和celecoxib同时给予的治疗反应,在被诊断为CP/CPPS的男性患者中.
- 为了确定影响这种联合治疗的患者减轻疼痛的因素.
主要方法:
- 一组96名40岁以下的CP/CPPS男性患者接受了一个月的tamsulosin (0.4 mg),levofloxacin (500 mg) 和celecoxib (200 mg) 疗程.
- 收集了患者数据,包括年龄,体重,BMI,吸烟状况,前列腺炎家族病史和教育状况.
- 治疗反应,定义为缓解疼痛,在一个月后进行评估并进行统计分析.
主要成果:
- 大约42.7%的患者在一个月的治疗期后报告疼痛缓解.
- 对于年龄,吸烟状况和前列腺炎家族病史,观察到与减轻疼痛的显著关联.
- 对缓解疼痛的负面影响包括体重增加 (OR=0.303),BMI增加 (OR=0.476) 和吸烟 (OR=0.801).
结论:
- 坦苏洛辛,莱沃素和塞莱科克西布的联合使用在缓解CP/CPPS患者症状方面表现出可接受的疗效.
- 该研究强调了可能影响患者群体治疗结果的潜在影响因素.
更多相关视频
06:44Demonstration of Cutaneous Allodynia in Association with Chronic Pelvic Pain
Published on: June 23, 2009
19.6K
07:20Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
Published on: December 21, 2012
15.9K
相关概念视频
01:21Drugs for Treatment of Constipation-Predominant IBS
130
Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
130
01:25Analgesia and Pain Management
443
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
443
01:17Drugs for Treatment of Diarrhea-Predominant IBS
142
Diarrhea-predominant irritable bowel syndrome (IBS-D) is a subtype of IBS characterized primarily by frequent, loose, or watery stools, abdominal pain, and abdominal discomfort. Therapeutic approaches to managing IBS-D include dietary changes, stress management techniques, and pharmaceutical interventions.
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
142
01:29Chronic Pancreatitis II: Collaborative Care
60
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
60