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美国国立卫生研究院分子探针ML283的类似物是强大的SARS-CoV-2酶抑制剂

David N Frick1, Robert V Bavisotto1, Nicholas C Hopper1

  • 1Department of Chemistry & Biochemistry, The University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53217, United States.

ACS chemical biology
|February 6, 2025
PubMed
概括

型肝炎病毒 (HCV) 螺旋酶抑制剂ML283及其类型显示出SARS-CoV-2 nsp13螺旋酶的强烈抑制. 这一发现表明,针对SARS-CoV-2的抗病毒药物开发有潜在的新途径.

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