遵守地中海饮食和结直肠癌风险:在摩洛哥人口中进行的一项大型病例对照研究
Khaoula El Kinany1,2, Zineb Hatime2, Achraf El Asri1,2
1Higher Institute of Nursing Professions and Health Techniques, Fez, Morocco.
Public health nutrition
|February 6, 2025
概括
坚持地中海饮食 (MD) 显著降低了结直肠癌 (CRC) 的风险,包括结肠和直肠癌亚型. 这一发现支持MD在癌症预防中的保护作用.
科学领域:
- 营养科学 营养科学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 地中海饮食 (MD) 与许多健康益处有关,包括降低癌症风险.
- 结肠直肠癌 (CRC) 在全球范围内仍然是一个重大的健康问题.
- 了解饮食对特定癌症亚型的影响对于公共卫生至关重要.
研究的目的:
- 调查遵守地中海饮食 (MD) 与患结直肠癌 (CRC) 亚型风险之间的关联.
- 评估MD在摩洛哥成年人群中的保护作用.
主要方法:
- 一个匹配的病例控制研究,涉及1516名CRC患者和1516名对照.
- 使用经过验证的食物频率问卷 (FFQ) 进行饮食评估.
- 使用0-10分数量化对MD的坚持,分为低,中,高坚持.
主要成果:
- 对MD的高度坚持 (得分6-9) 与CRC风险降低有关 (ORa = 0.74).
- 对结肠癌 (ORa = 0.74) 和直肠癌 (ORa = 0.73) 均观察到显著的风险降低.
结论:
- 这项研究提供了证据,支持地中海饮食对结直肠癌的保护作用.
- 这些发现加强了MD在地中海南部人口癌症预防中的作用.
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