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Updated: May 29, 2025

A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds
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基于KEAP1/NRF2/HO-1突变介导上调基因和生物信息分析的肺腺癌预后模型的构建

Wei Zhu1, Ye Zhang1, Lingyun Yang2

  • 1Department of Pathology, Xishan People's Hospital of Wuxi City, Wuxi, Jiangsu 214105, P.R. China.

Oncology letters
|February 6, 2025
PubMed
概括

这项研究确定了与KEAP1/NRF2/HO-1途径相关的四基因特征 (KNHMUGs),该特征可以预测肺腺癌 (LUAD) 的预后. 这种签名还有助于评估LUAD患者的免疫治疗反应和化疗敏感性.

关键词:
凯尔奇类似于ECH相关蛋白1/核因子红色素2相关因子2/血红素酶1相关因子药物预测 药物预测免疫疗法 免疫疗法肺部腺癌的癌症.突变是一种突变.预测模型的预测模型.瘤免疫微环境是一个微环境.

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