位置阻塞性睡眠呼吸暂停的社区流行率
Brett L Duce1,2, Antti E Kulkas3,4, Timo T Leppänen4,5,6
1Sleep Disorders Centre, Department of Respiratory & Sleep Medicine, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia.
概括
位置阻塞性睡眠呼吸暂停 (POSA) 在一般人群中比非位置阻塞性睡眠暂停更为常见. 卧卧主导的OSA亚型 (spOSA) 较为普遍,与卧卧孤立的OSA (siOSA) 相比,与更糟糕的健康结果有关.
科学领域:
- 睡眠医学 睡眠医学
- 呼吸系统医学 呼吸系统医学
- 心脏病学 心脏病学
背景情况:
- 位置性阻塞性睡眠呼吸暂停 (POSA) 的患病率和亚型需要进一步的社区研究.
- 了解卧底主要的OSA (spOSA) 和卧底孤立的OSA (siOSA) 的临床特征至关重要.
研究的目的:
- 在一个社区样本中调查POSA与非定位OSA的患病率.
- 探索POSA的临床特征和亚型,特别是spOSA和siOSA.
主要方法:
- 从睡眠心脏健康研究中对1870名参与者的横截面分析.
- 阻塞性睡眠呼吸暂停 (OSA) 定义为呼吸暂停-呼吸暂停指数 (AHI) ≥5次/h.
- POSA按卧床AHI ≥2x非卧床AHI进行分类;其他被归类为非定位OSA.
主要成果:
- POSA比非定位OSA (38%) 更普遍 (62%),躺卧和AHI总数更高.
- 患有POSA的参与者年龄较大,不太肥胖,并患有较高的缩血压.
- 上主导的OSA (spOSA) 比上孤立的OSA (siOSA) 更常见,并且与更糟糕的健康结果相关,包括高血压和糖尿病.
结论:
- 在睡眠心脏健康研究的人群中,POSA比非定位性OSA更为普遍.
- 与siOSA相比,spOSA亚型更常见,并与较差的健康后果有关.
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