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Updated: May 29, 2025

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
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基因表达的巨大变化及其原因可以成为阿尔茨海默氏症病理生物学中的统一原则

Paul D Coleman1, Elaine Delvaux1, Jeffrey H Kordower1

  • 1Banner Neurodegenerative Disease Research Center, Biodesign Institute, Arizona State University, Tempe, Arizona, USA.

Alzheimer's & dementia : the journal of the Alzheimer's Association
|February 6, 2025
PubMed
概括

阿尔茨海默病涉及广泛的基因表达变化. 一个统一的模型表明压力颗粒和改变的核细胞质运输是关键机制,为早期检测和干预提供了途径.

关键词:
阿尔茨海默病的疾病阿尔茨海默病的疾病.在RNAseqqq中使用.氨基ββββββββββββββββββββββββ基因表达的基因表达方式核孔复合体是核孔复合体.核细胞质体运输是核细胞质体运输.压力颗粒是压力颗粒.陶的纠结 陶的纠结

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