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Updated: Jun 14, 2025

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
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在SORBS2中一种新的误解变体是家族性阿尔茨海默病的致病因

Qi Wang1, Shiyuan Wang1, Shuman Cao1

  • 1Innovation Center for Neurological Disorders and Department of Neurology, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Diseases, Beijing, People's Republic of China.

CNS neuroscience & therapeutics
|February 6, 2025
PubMed
概括

一种新的SORBS2基因变异 (T189M) 与中国一家的家族性早期阿尔茨海默病 (AD) 有关. 这种基因突变促进神经炎症和神经元损伤,有助于AD的发病.

关键词:
在SORBS2中,我们可以使用SORBS2.阿尔茨海默病的疾病阿尔茨海默病的疾病.神经炎症是一种神经炎症.病理机制的病理机制.

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