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Updated: May 29, 2025

Intracranial Pharmacotherapy and Pain Assays in Rodents
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作为MOR-NMDAR交叉调节和非阿片类止痛药的选择性调节剂的HINT1抑制剂

Maxwell Dillenburg1, Cristina D Peterson2,3,4, Rafal Dolot5

  • 1Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.

ACS chemical neuroscience
|February 6, 2025
PubMed
概括

人类歇斯蒂丁三核酸结合蛋白1 (HINT1) 抑制剂调节片和NMDA受体相互作用. 这些新型化合物通过选择性向特定途径而未影响阿片类药物耐受性,显示出治疗疼痛的潜力.

关键词:
暗示 暗示 暗示没有NMDAR,没有NMDAR.止痛药 止痛药 止痛药是一种止痛药.-阿片类受体的受体对阿片类药物的耐受性

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