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Updated: Jul 10, 2026

Ex vivo Imaging of T Cells in Murine Lymph Node Slices with Widefield and Confocal Microscopes
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人类下淋巴结透的协议ex vivo以实时研究结构和功能.

Amy Llewellyn1, Rachel Barrow-McGee2, Julia Stevenson3

  • 1Translational Pathology, Comprehensive Cancer Centre, School of Cancer and Pharmaceutical Sciences, King's College London, London, UK.

STAR protocols
|February 6, 2025
PubMed
概括

研究人员开发了一种新方法,可以使人体淋巴结在体外保持24小时的活力. 这种技术允许详细研究淋巴结结构和功能在各种疾病和药物反应.

关键词:
癌症 癌症 癌症 癌症免疫学 免疫学 免疫学组织工程是组织工程.

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Detailed Structure and Function of Lymph Nodes01:23

Detailed Structure and Function of Lymph Nodes

Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...