在人类受影响的农产品中出现"潜伏"的抗生素耐药性
Chagai Davidovich1,2, Kseniia Erokhina1,2, Chhedi Lal Gupta3
1Institute of Soil, Water and Environmental Sciences, Agricultural Research Organization- Volcani Institute, Rishon LeZion, 7505101, Israel.
The ISME journal
|February 6, 2025
概括
农业中的废水灌和肥修改可以隐藏沙拉中的危险病原体和抗生素耐药性基因. 这些"隐藏"的污染物通过食物链对人类健康构成隐藏的风险.
科学领域:
- 环境微生物学环境微生物学
- 农业科学 农业科学
- 食品安全 食品安全
背景情况:
- 可持续农业越来越依赖于经过处理的废水灌和肥修改,特别是在缺水和营养地区.
- 这些做法可能会在作物中传播病原体和抗菌素耐药性 (AMR) 决定因素,通过食物链对人类健康构成风险.
- 之前的研究表明,这些元素在环境中的生存率很低,但最近的一项发现表明,这些元素在检测水平以下的持续性和潜在的扩散.
研究的目的:
- 为了调查该事件的发生.
主要方法:
- 利用一个丰富平台模拟肠道条件.
- 采用了基于分子和培养的综合分析方法.
- 分析了用经过处理的废水灌和用家禽垃圾修改的菜.
主要成果:
- 丰富检测到临床相关的多抗药性病原体指标和许多抗生素耐药性基因在经过处理的废水灌和垃圾修改的菜中.
- 这些元素没有通过直接分析或在淡水灌样本中发现.
- 耐药的大肠杆菌分离物表明,多个耐药性基因的水平等离子体转移到敏感菌株.
结论:
- 强调了在受人类活动影响的农业环境中隐藏的病原体和AMR决定因素的隐藏风险.
- 表明目前的检测方法可能低估了与废水和便使用相关的微生物风险.
- 为增强农业生态系统的定量微生物风险评估模型提供了基础.
相关概念视频
Antibiotic Selection
52.2K
Overview
52.2K
Bacterial Transformation
55.1K
In 1928, bacteriologist Frederick Griffith worked on a vaccine for pneumonia, which is caused by Streptococcus pneumoniae bacteria. Griffith studied two pneumonia strains in mice: one pathogenic and one non-pathogenic. Only the pathogenic strain killed host mice.
Griffith made an unexpected discovery when he killed the pathogenic strain and mixed its remains with the live, non-pathogenic strain. Not only did the mixture kill host mice, but it also contained living pathogenic bacteria that...
Griffith made an unexpected discovery when he killed the pathogenic strain and mixed its remains with the live, non-pathogenic strain. Not only did the mixture kill host mice, but it also contained living pathogenic bacteria that...
55.1K
Genomic DNA in Prokaryotes
43.3K
The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
Genomic Diversity in Bacteria
Although bacterial genomes are much...
Genomic Diversity in Bacteria
Although bacterial genomes are much...
43.3K
Defense Against Bacterial Pathogens
1.4K
The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
1.4K


