多重高风险因素的怀孕:系统审查和元分析
Yue Zhang1, Weijie Ding2, Tingting Wu1
1School of Public Health, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Journal of global health
|February 6, 2025
概括
多重高风险妊娠因素 (MHFP) 影响全球12%的怀孕,在低收入和中等收入国家中患病率越来越高. 综合性孕产妇保健对预防和干预至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 怀孕期间的高风险因素可能会导致母亲和新生儿的不良结果.
- 现有的研究缺乏关于怀孕多重高风险因素 (MHFP) 的测量,原因和结果的综合.
研究的目的:
- 综合现有关于怀孕多重高风险因素 (MHFP) 测量,模式,原因和健康结果的研究.
- 通过元分析估计 MHFP 的综合流行率.
主要方法:
- 对2024年6月3日之前发表的研究进行了系统的数据库搜索.
- 使用了叙事综合方法,并补充了用于流行率估计的元分析.
- 进行了子组分析和元回归来探索异质性.
主要成果:
- 包括83项观察性研究 (2010-2024年),其中72%来自高收入国家.
- MHFP模式包括身体,精神,社会行为和怀孕史因素;同时存在的身体状况是最常见的.
- MHFP的综合流行率为12%,显示出低收入和中等收入国家 (LMICs) 的增长趋势和更高的发病率.
- 观察到MHFP测量的显著异质性.
- 大多数研究 (78%) 检查了短期结果;只有两个研究了长期影响.
结论:
- 关于MHFP的研究正在增长,但尚未完成,全球负担正在增加,特别是在LMICs.
- 孕产妇医疗保健系统需要向多学科,综合框架转变.
- 需要有效的预防和干预计划来支持母亲和儿童的健康.
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