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Updated: May 29, 2025

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies
09:08

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies

Published on: June 2, 2021

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选择性破坏Traf1/cIAP2相互作用减轻了炎症反应和类风湿性关节炎

Yitian Tang1, Fatemah Aleithan1, Sahib Singh Madahar2

  • 1School of Kinesiology and Health Science, Muscle Health Research Centre, York University, Toronto, Ontario, Canada.

Journal of autoimmunity
|February 6, 2025
PubMed
概括

针对TRAF1/cIAP2相互作用可以减少炎症和类风湿性关节炎的严重程度. 这项研究确定了破坏这种相互作用的特定突变,为炎症性疾病提供了新的治疗策略.

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A Cryo-pulverization Protocol for Processing Mouse Paws to Evaluate Molecular Pathways of Tissue Inflammation in a Collagen Induced Arthritis Model11:03

A Cryo-pulverization Protocol for Processing Mouse Paws to Evaluate Molecular Pathways of Tissue Inflammation in a Collagen Induced Arthritis Model

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