量化方法用于评估犬类退行性 mitra 门疾病中 mitra 吐重度的量化方法
B Del Nero1, B M Potter1, L C Visser1
1Department of Clinical Sciences, Colorado State University, Campus Delivery 1678, Fort Collins, CO 80523-1678, USA.
概括
在患有退行性心肌膜疾病 (DMVD) 的狗中,对心肌膜反 (MR) 严重性的定量评估显示,心声回声学方法之间的结果各不相同. 卷度和近接等速表面积 (PISA) 方法在MR评估中是不可互换的.
科学领域:
- 兽医心脏病学 兽医心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心血管成像 - 心血管成像
背景情况:
- 对 mitrale regurgitation (MR) 严重程度的定量评估对于管理退行性 mitrale 膜疾病 (DMVD) 是至关重要的.
- 新兴的MR手术疗法需要精确的严重程度分级.
- 心声学方法在兽医中通常用于MR评估.
研究的目的:
- 量化评估犬群DMVD不同阶段的MR严重程度.
- 评估两种心声回声学方法之间的一致性:体积测量 (辛普森方法) 和近接等速度表面积 (PISA).
- 为了评估这两种方法的测量变异性.
主要方法:
- 51只患有DMVD (B1,B2,C阶段) 的狗被前性地注册.
- 使用体积计和PISA心声学方法测量了吐体积 (RVol) 和吐分数 (RF).
- 布兰德-阿尔特曼分析评估了方法之间的一致性;类内相关系数 (ICCs) 评估了变化.
主要成果:
- 无论是体积测量方法还是PISA方法,在DMVD阶段的RVol和RF中都显示出显著的差异 (P<0.0001).
- 在RVol或RF的方法之间没有观察到比例偏差.
- 发现了很高的观察者内部和观察者间一致性 (ICC>0.75),除了PISA衍生的RF外.
结论:
- 对MR严重性的心声测量与狗的DMVD阶段相关.
- 评估MR的体积测量和PISA方法是不可互换的.
- 需要进一步的研究来确定这些定量措施的绝对准确性.
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