患有2型糖尿病的患者中风
Terri W Jerkins1, David S H Bell2
1Midstate Endocrine Associates, Nashville, Tennessee.
概括
2型糖尿病 (T2DM) 显著增加中风风险,并使结果恶化. 较新的建议和抗糖尿病药物在预防中风和改善T2DM患者的生活质量方面表现有前途.
科学领域:
- 神经学 神经学
- 内分泌学 在内分泌学.
- 心血管医学 心血管医学
背景情况:
- 2型糖尿病 (T2DM) 与正常血糖人相比,将中风风险提高1.5至3倍.
- 尽管有传统的风险因素控制,但T2DM患者的中风复发率较高,中风后生活质量较差.
研究的目的:
- 审查将T2DM与中风风险增加联系在一起的病理生理学.
- 总结传统和新型风险因子修改对T2DM中风预防的影响.
主要方法:
- 对T2DM和中风病理生理学的多个出版物的综述.
- 对传统和新兴风险因素修改策略的新出版物的分析.
主要成果:
- 精细的传统风险因素修改包括优化脂质和血压水平,以及抗凝方法.
- 新兴的抗糖尿病药物,如葡萄糖类-1受体激活剂和皮奥格利塔,在预防糖尿病患者初级和二级中风方面表现出有效性.
结论:
- 在全球范围内,中风是导致死亡和残疾的主要原因,T2DM加剧了风险和结果.
- 实施最新的建议和新的治疗策略可以显著改善T2DM患者中风的结果.
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