儿童和青少年的心肌工作的心声参考范围:元分析
Xander Jacquemyn1, Benjamin T Barnes2, Sruti Rao2
1Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium; The Blalock-Taussig-Thomas Pediatric and Congenital Heart Center, Department of Pediatrics, Johns Hopkins School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
International journal of cardiology
|February 6, 2025
概括
这项研究为儿童建立了正常心肌工作 (MW) 参考范围,这对儿科心脏病学至关重要. 调查结果证实了MW的MW.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心血管生理学心血管生理学
背景情况:
- 确定左心室心肌工作 (MW) 的儿科参考值对于临床应用至关重要.
- 心肌工作指数包括全球工作指数 (GWI),全球建设性工作 (GCW),全球浪费工作 (GWW) 和全球工作效率 (GWE).
研究的目的:
- 为健康儿童提供正常的左心室肌动脉工作 (MW) 参考范围.
- 在儿科人群中涵盖全球工作指数 (GWI),全球建设性工作 (GCW),全球浪费工作 (GWW) 和全球工作效率 (GWE).
主要方法:
- 对报告健康儿童MW指数的研究进行系统的文献搜索,直到2024年2月.
- 用随机效应模型和对性别和地理差异的子组分析对加权平均值的元分析.
- 超回归以确定MW指数的调节器,包括年龄,血压和心率.
主要成果:
- 包括12项研究,涉及1037名儿童 (平均年龄10.7岁).
- 聚合的平均值:GWI 1525.4 mmHg%,GCW 1880.3 mmHg%,GW 57.2 mmHg%,GWE 96.8%. 没有任何其他数据.
- 没有显著的性别差异;在欧洲/美国和东亚队列之间,在GCW和GWW中发现了区域差异. 年龄,血压和HR是显著的调节器. 在观察者之间和观察者内部具有很好的可重复性 (ICCs 0.81-0.96).
结论:
- 提供了针对儿童的特定年龄的心肌工作参考范围.
- 这些范围对于儿科心脏病学中的临床和研究应用是有价值的.
- 证实了心肌工作测量在儿童中的可重现性.
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