在美国成年人中,平均每日睡眠时间和胆结石之间存在联系
Yong Fang1, Qiuyuan Xu1, Jia Xu1
1Affiliated XiaoShan Hospital of WenZhou Medical University (XiaoShan District First People's Hospital), No. 199, ShiXin South Road, XiaoShan District, HangZhou, 311200, ZheJiang Province, China.
Scientific reports
|February 6, 2025
概括
睡眠时间较短与成人胆结石患病率较高有关. 这项研究强调睡眠时间是胆结石发展的潜在因素,特别是在中年成人和糖尿病患者中.
科学领域:
- 流行病学 流行病学
- 睡眠医学 睡眠医学
- 胃肠病学 胃肠病学
背景情况:
- 虽然健康因素和睡眠得到了广泛的研究,但平均每日睡眠时间和成年人胆结石患病率之间的直接联系仍未得到充分研究.
- 胆结石 (胆结石) 是一种常见的胃肠道疾病,具有多因素的病因.
- 了解睡眠等可修改的风险因素对于公共卫生干预至关重要.
研究的目的:
- 调查代表性成年人群中平均每日睡眠时间和胆结石患病率之间的关联.
- 识别潜在的人口或与健康相关的子组,其中这种关联可能更明显.
主要方法:
- 分析了2017-2020年国家健康和营养检查调查 (NHANES) 7,441名参与者的数据.
- 排除标准的应用,以完善研究队列.
- 进行了多变量逻辑回归和子组分析,以控制潜在的混因素.
主要成果:
- 在平均每日睡眠时间和胆结石患病率 (OR = 0.92; 95% CI: 0.86, 0.99; p = 0.0236) 之间发现了统计学上显著的反向关联.
- 这种关联在各种人口统计和与健康有关的子组中保持一致.
- 在中年成年人 (40-60岁) 和糖尿病患者中发现了关联的拐点.
结论:
- 平均每日睡眠时间与成人胆结石的患病率相反相关.
- 睡眠管理可能是预防胆结石的新策略,特别是在中年人和糖尿病患者中.
- 需要进一步的研究来阐明这种关系背后的机制.
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