上眼内部的orbicularis oculi肌肉与年龄相关的变薄及其可能与沉没的上眼相关
Takamasa Gomi1, Itsuko Okuda2, Ami Seino3
1Frontier Research Center, POLA Chemical Industries Inc., 560 Kashio-cho, Totsuka-ku, Yokohama, Kanagawa, 244-0812, Japan. takag@pola.co.jp.
Scientific reports
|February 6, 2025
概括
老龄化导致眼上部下沉,原因是眼肌 (orbicularis oculi) 的变化. 这项研究将与年龄相关的肌肉纤维减少和结缔组织增加与眼形态联系起来.
科学领域:
- 眼科医生 眼科 眼科
- 人体解剖学 解剖学 解剖学
- 老年学是一门学科.
背景情况:
- 眼上方沉没是一种常见的衰老症状,原因不明.
- 了解周期性衰老机制对于审美和功能考虑至关重要.
研究的目的:
- 为了研究沉没的上眼lids和形态变化在periocular区域之间的关系.
- 为了将年龄与上眼lids沉没的程度相关联.
- 分析与衰老相关的眼肌组织学变化.
主要方法:
- 磁共振成像 (MRI) 用于评估眼皮的形态.
- 摄影分析以量化随着年龄的增长而下沉的眼.
- 在尸体中对orbicularis oculi肌肉纤维 (MYH物种) 和连接组织进行组织学检查.
主要成果:
- 沉没的上眼皮随着年龄的增长而发展.
- 随着年龄的增长,观察到眼肌中MYH4阳性肌肉纤维的厚度和数量减少.
- 随着年龄的增长,人们在眼肌 (orbicularis oculi) 肌肉中发现了原蛋白和弹性纤维的增加.
- 核磁共振扫描显示,上眼和眼肌肉厚度,以及地球位置之间存在负相关性.
结论:
- 眼肌的与年龄相关的变化,包括肌纤维损失和连接组织变化,有助于上眼沉没.
- 眼圈肌肉形态是与年龄相关的周期性变化的一个关键因素.
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