后急性COVID-19综合征中心血管症状的发生率:一个元分析
Li-Wei Huang1, Hua-Min Li1, Bei He1
1Department of Pharmacy, the Second Xiangya Hospital, Central South University, Changsha, Hunan, 410011, China.
BMC medicine
|February 6, 2025
概括
COVID-19 感染显著增加了心血管后果的风险,包括胸痛,心和高血压. 这一元分析强调了在感染后监测心脏健康的重要性.
科学领域:
- 心脏病学 心脏病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 在全球范围内,COVID-19对身体和精神健康构成重大威胁.
- 后急性COVID-19综合征 (PACS) 可能涉及心血管并发症.
- 关于PACS心血管表现的研究有限,这阻碍了治疗的发展.
研究的目的:
- 为了调查COVID-19患者心血管后果的患病率.
- 为了确定COVID-19感染是否是心血管结果的独立风险因素.
主要方法:
- 在PROSPERO (CRD42024524290) 中注册的PRISMA指导方针的元分析.
- 在PubMed,Embase和Cochrane图书馆进行系统搜索,截至2024年3月17日.
- 主要结局:高血压,心跳,胸痛. 聚合效应估计报告为比例和几率比率 (ORs) 与95%的置信区间 (CI).
主要成果:
- 对37项涉及2,965,467名患者的研究进行了分析.
- 与对照组相比,COVID-19患者的胸痛 (OR=4.0),心 (OR=3.4),高血压 (OR=1.7) 的几率较高.
- 患有后续症状的PACS患者的比例:胸痛 (22%),心 (18%),高血压 (19%).
结论:
- 大约15%的COVID-19患者经历了心血管疾病的后果.
- 感染COVID-19显著增加了患上这些后果的风险.
- 需要对病理机制和有针对性的管理策略进行进一步的研究.
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