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Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

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Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
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Negative Regulator Molecules01:23

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Positive regulators allow a cell to advance through cell cycle checkpoints. Negative regulators have an equally important role as they terminate a cell’s progression through the cell cycle—or pause it—until the cell meets specific criteria.
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Work is done on an object when energy is transferred to the object. In other words, work is done when a force acts on a body that undergoes a displacement from one position to another. By definition, the work done by a force is the integral of the force with respect to the displacement along its path. Forces can vary as a function of position, and displacements can occur along various paths between two points. The magnitude of a force multiplied by the cosine of the angle that the force makes...
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Animal organs and organ systems constantly adjust to internal and external changes through a process called homeostasis ("steady state"). Examples of these changes include regulation of the level of glucose or calcium in the blood or internal responses to external temperatures. Homeostasis requires  maintaining an internal dynamic equilibrium:
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Information is everywhere and its presentation—such as how and when items are presented—can impact our perceptions and decisions surrounding the info. This broad concept umbrellas framing effects—influences that occur due to the way information is framed in its appearance, whether it’s purely the order or the specific wording of a message. Let’s take a look at numerous ways in which two versions of something can objectively say the same thing, yet we respond in...
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Attitude is our evaluation of a person, an idea, or an object. We have attitudes for many things ranging from products that we might pick up in the supermarket to people around the world to political policies. Typically, attitudes are favorable or unfavorable: positive or negative (Eagly & Chaiken, 1993). And, they have three components: an affective component (feelings), a behavioral component (the effect of the attitude on behavior), and a cognitive component (belief and knowledge;...
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"这听起来非常消极"

Courtney Andrews1, Valerie M Lawhon1, Kimberly Wiseman2

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此摘要是机器生成的。

患有早期乳腺癌 (EBC) 的患者不喜欢化学疗法试验的"降级"一词. 他们更喜欢积极的语言,反映优化治疗,而不是减少护理,以便更好地共享决策.

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科学领域:

  • 在瘤学瘤学.
  • 临床试验设计 临床试验设计
  • 以患者为中心的沟通

背景情况:

  • 癌症研究的进展使得早期乳腺癌 (EBC) 的化疗强度降低.
  • 目标是保持无复发的生存率,同时最大限度地减少治疗毒性.
  • 临床试验对于确定最佳的,不那么强烈的化疗剂量至关重要.

研究的目的:

  • 评估患者和倡导者对EBC临床试验中的"降级"术语的反应.
  • 确定用于描述减少化疗方法的首选术语.
  • 改善关于治疗选择的沟通和共享决策.

主要方法:

  • 通过内容分析进行了患者调查和编码采访.
  • 分析了参与者对"降级"一词及其内涵的反应.
  • 收集了关于患者偏好的见解,用于描述治疗优化.

主要成果:

  • 参与者对"降级"一词做出了负面反应,将其与"放弃"联系起来.
  • 确定了对积极,以患者为中心的语言的偏好.
  • 负面反应强调需要谨慎的沟通策略.

结论:

  • "降级"一词可能会阻碍患者的入学和对EBC临床试验的理解.
  • 使用积极的,以患者为中心的语言对于有效的沟通至关重要.
  • 改进的术语可以防止治疗误解,并支持共享决策.