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Updated: May 29, 2025

A Protocol for Computer-Based Protein Structure and Function Prediction
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AlphaFold2和ESMFold:在Pfam功能注释上对人类酶进行大规模对对模型比较

Matteo Manfredi1,2, Gabriele Vazzana1,2, Castrense Savojardo1,2

  • 1Biocomputing Group, University of Bologna, Italy.

Computational and structural biotechnology journal
|February 7, 2025
PubMed
概括

AlphaFold2和ESMFold准确地模拟了具有已知的功能 (Pfam域) 的蛋白质区域. 这两种方法都对这些区域具有很高的信心,有助于发现新的酶活性位点.

关键词:
在AlphaFold2中,我们使用了AlphaFold2.在ESMFold.酶活性部位 酶活性部位人类参考蛋白质组人类酶结构和功能注释Pfam 域名 家庭域名

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