童年创伤对双相情感障碍患者认知功能的影响
Zhiyang Zhang1,2, Chenyu Zhou1,2, Zhen Mao1,2
1The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders & Beijing Institute for Brain Disorders Center of Schizophrenia, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Frontiers in psychiatry
|February 7, 2025
概括
童年创伤在双相情感障碍 (BD) 患者中更常见,并影响认知. 特别是情绪虐待,预测记忆力较差,突出创伤.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 认知心理学 认知心理学
背景情况:
- 双极性障碍 (BD) 经常与认知障碍有关.
- 儿童创伤作为BD风险因素和随后的认知缺陷之间的联系需要进一步澄清.
研究的目的:
- 调查儿童创伤和被诊断患有双相情感障碍的患者的认知功能之间的关系.
主要方法:
- 该研究涉及90名BD患者和94名健康对照 (HC).
- 儿童创伤使用儿童创伤问卷 (CTQ) 进行评估.
- 使用可重复电池评估神经心理状态 (RBANS) 评估认知功能.
主要成果:
- 与HC相比,BD组的儿童虐待和忽视在BD组中更为普遍.
- 情绪虐待与直接记忆力受损有关.
- 药物使用显示出各种认知关联:情绪稳定剂与语言正相关,而抗精神病药物对注意力产生负面影响.
结论:
- 童年创伤在患有BD的个体中更频繁,并对认知领域产生差异影响.
- 了解BD中这些创伤认知联系对于开发有针对性的干预措施至关重要.
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