低流氧输送使用鼻腔管在全身麻醉下接受选择性手术的儿童中进行无呼吸氧化:一项随机对照试验
Sohini Ray1, Anju R Bhalotra1, Mona Arya1
1From the Department of Anaesthesiology & Intensive Care, Maulana Azad Medical College and Associated Hospitals (SR, ARB, MA) and Department of Anaesthesiology, Vardhaman Mahavir Medical College and Safdarjung Hospital, New Delhi, India (KRS).
European journal of anaesthesiology and intensive care
|February 7, 2025
概括
通过鼻腔管进行无呼吸氧化,有效地防止了在输管过程中儿童的氧气不和. 与对照组相比,这种方法保持了较高的氧和水平,确保了患者的安全.
科学领域:
- 儿科麻醉学 儿科麻醉学
- 呼吸系统生理学 呼吸系统生理学
- 关键护理医学 关键护理医学
背景情况:
- 由于肺体积较小和代谢率较高,儿童在呼吸暂停期间患氧气低血的风险更高.
- 在接受喉腔镜检查和输管治疗的儿科患者中,无呼吸氧化疗法的有效性仍未得到充分研究.
研究的目的:
- 评估鼻腔管无呼吸氧化的有效性,以防止儿童在喉腔镜检查和输管检查期间缺氧.
- 为了比较接受无呼吸氧化治疗的儿童和对照组之间的外周氧和 (SpO2) 水平.
主要方法:
- 一项前性,随机,双盲控制试验与120名1-6岁儿童进行.
- 参与者被分配通过鼻腔 (无呼吸氧化组) 接受3L/分钟的氧气,或没有氧气 (对照组).
- 在喉腔镜检查和输管治疗期间的 SpO2 最低值是主要结局;二次结局包括 SpO2 降低和胸发病率.
主要成果:
- 与对照组 (98.37% ± 4.60%;P=0.009) 相比,无呼吸氧化组保持了显著更高的最低 SpO2 (99.95% ± 0.29%).
- 无呼吸氧化组中没有患者经历过SpO2下降,尽管无呼吸时间较长 (P=0.012).
- 在对照组中,4名患者的SpO2下降到92%以下 (P=0.038),并且在两组中都没有观察到胸心梗塞.
结论:
- 通过鼻腔管进行无呼吸氧化是一种有效的策略,可以预防儿科患者在喉腔镜检查和输管治疗期间的氧气不和.
- 这种干预显著改善了在全身麻醉下接受呼吸道手术的儿童的氧化安全.
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