生命的基本8分数和COPD风险之间的剂量反应关系:NHANES队列研究2007-2018年
Qian Huang1, Quan Yuan2, Wenqiang Li2
1Dazhou Dachuan District People's Hospital (Dazhou Third People's Hospital), Dazhou, Sichuan, China.
Frontiers in medicine
|February 7, 2025
概括
更高的生活必需品8 (LE8) 评分与患慢性阻塞性肺病 (COPD) 的风险较低有关. 这种反向关系表明,改善心血管健康可能会防止COPD,特别是在40岁以上的人群中.
科学领域:
- 心血管健康和呼吸系统疾病
- 公共卫生和流行病学
背景情况:
- 慢性阻塞性肺病 (COPD) 是一个主要的全球健康问题.
- 心血管健康越来越被认为是影响呼吸系统健康的因素.
- 生活必需品8 (LE8) 评分是对心血管健康的综合衡量.
研究的目的:
- 为了研究LE8得分和COPD风险之间的剂量反应关系.
- 为了确定心血管健康,以LE8测量,是否会影响COPD的流行.
主要方法:
- 分析来自国家健康和营养检查调查 (NHANES) 数据库 (2007-2018) 的数据.
- 利用后勤回归和子组分析来评估LE8分数和COPD之间的关联.
- 使用限制立方线 (RCS) 图表来可视化剂量反应关系.
主要成果:
- 总共有12,517名参与者被分析,其中835人被诊断为COPD.
- 在多变量调整后,在较高的LE8得分和降低的COPD风险之间发现了显著的,线性和反向的关联.
- LE8得分的健康行为组件与COPD风险的反向关系比健康因素组件更强.
结论:
- 较高的LE8分数独立地与患上COPD的可能性降低有关.
- 通过生活方式因素改善心血管健康,正如LE8所示,可以作为COPD的预防策略,特别是在40岁以上的成年人中.
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