生物丁对Enterococcus faecalis的抗菌活性:一个系统的审查
Hasan Subhi1, Nashwah Subhi2, Salah Alhaidary3
1School of Dental Sciences, Universiti Sains Malaysia, Kelantan, Malaysia.
Frontiers in dental medicine
|February 7, 2025
概括
生物牙显示出良好的抗菌活性,可以对抗Enterococcus faecalis,这是内牙失败的常见原因. 这次审查发现Biodentine与许多其他内牙材料同样有效或更有效.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 牙科材料科学 牙科材料科学
- 微生物学 微生物学
背景情况:
- 生物牙是一种广泛使用的内牙材料.
- 菌 (Enterococcus faecalis) (E. faecalis) 与内牙治疗失败和持续的周围感染有关.
研究的目的:
- 系统地审查和总结Biodentine对E. faecalis.抗菌活性的证据.
- 为了比较Biodentine对E. faecalis的疗效与其他商业内牙材料.
主要方法:
- 在主要数据库 (PubMed,Scopus,Web of Science,Google Scholar) 和期刊中进行了全面的文献搜索,截至2024年5月.
- 两个独立的审稿人评估了研究的资格,提取了数据,并使用用于临床前体外研究的修改后的CONSORT检查清单项目评估了偏差风险.
主要成果:
- 37项研究符合纳入标准,其中30项报告了Biodentine对E. faecalis的良好抗菌疗效.
- 生物牙证明了优越或与许多其他材料相比的有效性,包括MTA,GIC,RMGIC和各种基于酸的水泥.
- 研究结果得到了中高偏差风险的证据支持,这表明总体质量低.
结论:
- 越来越多的证据表明,Biodentine在内牙科环境中对E. faecalis具有抗菌活性.
- 需要进一步进行高质量的随机临床试验,以验证Biodentine的临床性能和行为.
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