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Updated: May 29, 2025

A Facile Protocol to Generate Site-Specifically Acetylated Proteins in Escherichia Coli
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在蛋白质多样化和毒性分析中,通过阿克罗林介导的氨酸转化为电友异环

Zachary E Paikin1, Benjamin Emenike1, Rajendra Shirke1

  • 1Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States.

Journal of the American Chemical Society
|February 7, 2025
PubMed
概括

这项研究引入了一种新的化学反应, 选择性地修改蛋白质上的氨酸残留物, 创建高级蛋白质工程和标签的独特结构. 这一发现有助于理解蛋白质相互作用和蛋白诱导的修饰.

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