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Fluorescence Assays for the Study of Mycobacterium tuberculosis Interaction with the Immune Receptor SLAMF1
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不同的化学支架与Mycobacterium tuberculosis Phe-tRNA合成酶中的L-phe位点结合

Priyanka Gade1, Changsoo Chang1, Denise S Pryde2

  • 1Center for Structural Biology of Infectious Diseases, Consortium for Advanced Science and Engineering, University of Chicago, Chicago, IL, 60667, USA; Structural Biology Center, X-ray Science Division, Argonne National Laboratory, Lemont, IL, 60439, USA.

European journal of medicinal chemistry
|February 7, 2025
PubMed
概括

鉴定出了针对Mycobacterium结核菌甲-tRNA合成酶 (MtPheRS) 的新片段. 这些碎片与L-Phe部位结合,为开发针对耐药菌株的新型抗结核药物提供了洞察力.

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