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Updated: May 29, 2025

In Vitro SUMOylation Assay to Study SUMO E3 Ligase Activity
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Published on: January 29, 2018

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SUMOylation 调节了 GSDMD 的稳定性和热的发生

Yuhua Shi1, Xinyue Li1, Weilv Xu1

  • 1MOA Key Laboratory of Animal Virology, Center for Veterinary Sciences, Zhejiang University, Hangzhou 310058, Zhejiang, China; Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310058, Zhejiang, China.

International immunopharmacology
|February 7, 2025
PubMed
概括

小型泛素类修饰剂 (SUMO) 化通过影响Gasdermin D (GSDMD) 的表达和活性来调节热. 抑制SUMOylation或向SENP3为炎症性疾病提供了潜在的治疗策略.

关键词:
加斯德明 D D D炎症性酶体 (inflammasomes) 是一种炎症性酶体.热灭菌的发生.在 SUMO/SUMO 基化过程中,

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