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在怀孕期间治疗CIN 2-3时使用LEEP的安全性
Yoav Siegler1, Jacob Bornstein, Ofer Lavie
1Departments of Obstetrics & Gynecology, Rambam Health Care Campus-Haifa, Haifa, Israel.
Journal of lower genital tract disease
|February 7, 2025
概括
循环电外科切割手术 (LEEP) 对于怀孕后15周内进行时,对于患有宫内皮质瘤 (CIN) 2-3的孕妇是安全的. 大多数怀孕继续到期,少数人被诊断患有侵袭性宫癌.
科学领域:
- 妇科 妇科医生 妇科
- 产科 产科 产科 产科 产科
- 在瘤学瘤学.
背景情况:
- 宫内皮质瘤 (CIN) 2-3是一种前发性疾病.
- 孕妇中CIN 2-3的管理与非孕妇不同.
- 循环电外科切除手术 (LEEP) 是对CIN2-3的标准治疗方法.
研究的目的:
- 评估怀孕期间CIN 2-3的循环电外科切除程序 (LEEP) 的安全性和结果.
- 评估LEEP对妊娠延续和分娩的影响.
- 为了确定孕妇中CIN 2-3的进展,保守地管理.
主要方法:
- 从2006年到2023年,对178名患有CIN 2-3的孕妇进行了回顾性数据分析.
- 在怀孕15周内接受LEEP的妇女与保守管理的妇女之间的结果比较.
- 关于怀孕,分娩和CIN状态的后续数据.
主要成果:
- 在怀孕15周内,LEEP对67名孕妇进行,仅有轻微的并发症.
- 在LEEP后的57个持续怀孕中,93%的孕妇在预产期分娩.
- 在没有LEEP的女性中,5.2%最终被诊断为侵袭性宫癌,而76.3%仍然是CIN 2-3.
结论:
- 循环电外科切除手术 (LEEP) 是一个安全的选择,用于在怀孕的第一个15周内在孕妇中管理CIN 2-3.
- 在怀孕期间对CIN 2-3进行保守的管理,会有进展到侵袭性癌症的风险.
- 对于CIN2-3的孕妇来说,仔细监测和个性化治疗决定至关重要.
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