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Updated: May 29, 2025

Two- and Three-Dimensional Live Cell Imaging of DNA Damage Response Proteins
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Published on: September 28, 2012

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PICH通过其DNA转位酶和SUMO相互作用活动对螺旋组装检查点产生影响

Bunu Lama1, Hyewon Park1, Anita Saraf2

  • 1Department of Molecular Biosciences, University of Kansas, Lawrence, KS, USA.

Life science alliance
|February 7, 2025
PubMed
概括

动态线粒体SUMOylation对于基因组完整性至关重要. 波罗样酶1相互作用检查点酶 (PICH) 调节SUMOylated蛋白质,其缺陷激活了螺旋组装检查点 (SAC),影响了线粒分裂.

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