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Updated: May 29, 2025

Two Flow Cytometric Approaches of NKG2D Ligand Surface Detection to Distinguish Stem Cells from Bulk Subpopulations in Acute Myeloid Leukemia
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Two Flow Cytometric Approaches of NKG2D Ligand Surface Detection to Distinguish Stem Cells from Bulk Subpopulations in Acute Myeloid Leukemia

Published on: February 21, 2021

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通过核受体NR2F6F6调节NK细胞的发育,成熟和抗瘤反应

Johannes Woelk1, Florian Hornsteiner2, Stephanie Aschauer-Wallner3,4

  • 1Institute of Cell Genetics, Department for Genetics and Pharmacology, Medical University of Innsbruck, Innsbruck, Austria.

Cell death & disease
|February 7, 2025
PubMed
概括

核孤儿受体NR2F6抑制NKp46,对自然杀手 (NK) 细胞细胞毒性至关重要. 缺乏NR2F6会损害NK细胞成熟和抗瘤免疫力,但IL-15疗法可以恢复功能并增强瘤监测.

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