在心脏病和T2DM患者中进行血糖控制的远程医疗支持的生活方式干预:多中心,随机对照试验
Stephan Mueller1,2, Sophia M T Dinges1,2, Felix Gass1,2
1Technical University of Munich, School of Medicine and Health, Department for Preventive Sports Medicine and Sports Cardiology, TUM University Hospital, Munich, Germany.
Nature medicine
|February 7, 2025
概括
通过远程医疗支持的生活方式干预,在6个月内,冠状动脉疾病和2型糖尿病患者的糖化血红蛋白略有改善. 当强化支持被移除时,效果会减少,这突显了对心血管健康持续干预的需要.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 数字健康数字健康
背景情况:
- 患有冠心病 (CHD) 和2型糖尿病 (T2DM) 的患者面临心血管事件和死亡率的风险增加.
- 饮食和运动等生活方式的修改可以减少心血管风险因素,但它们的效果往往是暂时的.
研究的目的:
- 评估家庭远程医疗支持的生活方式干预对结合性心脏病和T2DM患者的疗效.
- 评估干预对心血管风险因素和主要心血管不良事件的影响.
主要方法:
- 一个多中心,随机对照试验,涉及502名患有心脏病和T2DM的患者.
- 干预组接受了基于家庭的远程医疗计划,包括运动,营养和健康素养培训,并提供个性化的反.
- 对照组接受了通常的护理.
主要成果:
- 生活方式干预组在6个月后显示出糖化血红蛋白 (HbA1c) 的统计学显著降低 (平均差异为-0.13%,P=0.04).
- 在停止个性化反和健康素养培训后的12个月内,这种益处没有持续下去.
- 在12个月后,研究小组之间没有观察到主要不良心血管事件或死亡率的显著差异.
结论:
- 通过远程医疗支持的家庭生活方式干预表明,在患有心脏病和T2DM的患者中,对血糖控制有适度的益处.
- 这些好处的可持续性似乎取决于持续的密集支持,包括个性化的反和健康素养培训.
- 需要进行进一步的研究,以优化远程医疗干预措施,以便在这一群体中长期控制心血管风险.
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