美国成年人第一次胆囊切除术时的血压,胆结石和年龄:一个横截面研究
Yue Zhang1, Ruifeng Duan1, Xin Chen1
1Department of Gastroenterology and Digestive Endoscopy Center, The Second Hospital of Jilin University, Changchun, PR China.
BMC gastroenterology
|February 7, 2025
概括
高血压与超过42岁的成年人以及更早的胆囊切除手术年龄的胆结石患病率较高有关. 这项研究有助于识别有胆结石疾病风险的个体.
科学领域:
- 胃肠病学 胃肠病学
- 心脏病学 心脏病学
- 流行病学 流行病学
背景情况:
- 胆结石是一个重大的公共卫生问题.
- 新出现的证据表明,血压和胆结石形成之间存在联系.
- 这项研究研究了美国成年人中高血压和胆结石疾病患病率以及第一次胆囊切除术的年龄之间的关系.
研究的目的:
- 评估高血压和胆结石患病率之间的关联.
- 检查高血压与第一次胆囊切除术时的年龄之间的关系.
- 确定潜在的风险因素,并为胆结石疾病的早期检测策略提供信息.
主要方法:
- 利用了来自国家健康和营养检查调查 (NHANES) 数据库 (2017-2020) 的数据.
- 采用加权后勤和线性回归,通用添加模型 (GAM) 和顺曲线.
- 应用了两部分线性回归模型来确定缩血压在第一次胆囊切除术时的年龄上的拐点.
主要成果:
- 包括7,532名美国成年人;817人报告了胆囊切除术史,781人报告了胆结石史.
- 高血压在48岁 (OR=1.39) 个体中与胆结石有显著的关联.
- 静脉血压与第一次胆囊切除术时的年龄正相关 (β=0.20),转折点为170mmHg.
结论:
- 在42岁及以上的成年人中,血压和胆结石患病率之间存在相关性.
- 系统性血压与第一次胆囊切除术的年龄有关.
- 这些发现可能有助于对胆结石疾病和胆囊切除术的早期风险分层,从而可能降低查成本.
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