电子烟和香烟使用与自我报告的慢性阻塞性肺病 (COPD) 的关联:对美国大型数据集的多变量分析
Alicia J Burns1, Alexander W Steinberg2, James D Sargent3
1Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA. alicia.j.burns@hitchcock.org.
Respiratory research
|February 7, 2025
概括
前吸烟者目前使用电子烟与更高的慢性阻塞性肺病 (COPD) 风险有关. 然而,这个协会,这个协会.
科学领域:
- 肺部医学 肺部医学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 之前的研究表明,电子烟使用与慢性阻塞性肺病 (COPD) 之间存在联系.
- 这项研究调查了电子烟使用与老年人中COPD患病率之间的关系,考虑到他们的吸烟史.
研究的目的:
- 检查各种烟草和电子烟使用模式与COPD患病率之间的关联.
- 评估吸烟史上的不同建模方法对COPD风险估计的影响.
主要方法:
- 利用了来自2020年全国健康访谈调查 (N=22,997) 对40岁以上成年人的数据.
- 采用加权的多变量分析,考虑人口统计,并发性疾病和详细的吸烟史 (包装年,发病年龄).
- 通过将戒烟以来的几年,吸烟强度和持续时间纳入模型来评估结果的敏感性.
主要成果:
- 在以前的吸烟者中,目前的电子烟使用者表现出明显更高的COPD流行率 (ARR 2.82).
- 这种关联对吸烟史的建模敏感;自戒烟或吸烟持续时间以来的几年调整减轻了风险.
- 根据分析模型,香烟和电子烟使用的其他组合也表明了COPD风险的变化.
结论:
- 前吸烟者目前使用电子烟与COPD患病率的增加有关.
- 这些发现的稳定性受到质疑,因为对吸烟史的建模方式的敏感性.
- 在横截面研究中反向因果关系的可能性需要进一步调查.
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