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Updated: May 29, 2025

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使用特定混合IC-LC-MS/MS方法对临床样本中的抗药抗体进行深入的表征和半量化

Stéphane Muccio1, Christophe Hirtz2, Daniel Kramer3

  • 1Sanofi, TMED-BCB, 371 rue du Professeur Blayac, 34184 Montpellier, France.

Analytical biochemistry
|February 8, 2025
PubMed
概括

评估免疫性对于生物疗法至关重要. 一种新的质谱法检测抗药抗体同型,提供详细的免疫反应特征,并有助于预测不良事件.

关键词:
一个助理律师.免疫性 免疫性 免疫性确定异型的方法这种混合LC-MS系统.免疫捕获 免疫捕获 免疫捕获质谱测量质谱测量质谱测量质谱测量质量测量质谱测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量质量测量

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相关概念视频

Mass Spectrometry: Complex Analysis01:21

Mass Spectrometry: Complex Analysis

Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
GC–MS is a powerful hyphenated method commonly used in forensics and environmental...
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